
Deferoxamine
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
70-51-9
Deferoxamine B, Deferrioxamine
C13057-1mg
HIF
Angiogenesis
C25H48N6O8
Deferoxamine (Deferoxamine B, Deferrioxamine) is an iron chelator and a reversible inhibitor of S-phase in DNA synthesis. It enhnaces HIF-1α activation by inhibiting prolyl hydroxylase activity, activating insulin receptor (InsR) and Glut1. It also increases phosphorylation of Akt/PKB, FoxO1, GSK3β, influencing gluconeogenesis and glycogen synthesis, while reducing oxidative stress in diabetic hyperglycemia. It can be used to reduce iron accumulation and deposition in tissues and in studies of neurodegenerative diseases, anti-cancer and anti-COVID-19.
Beschrijving
Deferoxamine Beschikbaar in 1 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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