Dehydrodiisoeugenol-d4

Dehydrodiisoeugenol-d4 is the deuterium labeled Dehydrodiisoeugenol. Dehydrodiisoeugenol can found in Myristica fragrans Houtt, shows anti-inflammatory and anti-bacterial actions. Dehydrodiisoeugenol inhibits LPS- stimulated NF-κB activation and cyclooxygenase (COX) -2 gene expression in murine macrophages[1][2].

12352005

Bacterial; COX; Isotope-Labeled Compounds; NF-κB

Anti-infection; Immunology/Inflammation; NF-κB; Others

Infection; Inflammation/Immunology

OC1=CC=C(C2OC3=C(OC)C=C(/C=C([2H])/C([2H])([2H])[2H])C=C3C2C)C=C1OC

C20H18D4O4

330.41

[1]Murakami Y, et al. Dehydrodiisoeugenol, an isoeugenol dimer, inhibits lipopolysaccharide-stimulated nuclear factor kappa B activation and cyclooxygenase-2 expression in macrophages. Arch Biochem Biophys. 2005 Feb 15;434 (2) :326-32. |[2]Lv QQ, et al. Metabolic profiling of dehydrodiisoeugenol using xenobiotic metabolomics. J Pharm Biomed Anal. 2017 Oct 25;145:725-733.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-N0589S/

Isotope-Labeled Compounds

No Development Reported