Delta Sarcoglycan (SGCD) (NM 000337) Humaan Recombinant eiwit

The protein encoded by this gene is one of the four known components of the sarcoglycan complex, which is a subcomplex of the dystrophin-glycoprotein complex (DGC) . DGC forms a link between the F-actin cytoskeleton and the extracellular matrix. This protein is expressed most abundantly in skeletal and cardiac muscle. Mutations in this gene have been associated with autosomal recessive limb-girdle muscular dystrophy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Jul 2008]

Purified recombinant protein of Human sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) (SGCD), transcript variant 1, Gly66-End, with N-terminal His tag, expressed in E. coli, 50ug

35DAG; CMD1L; DAGD; LGMDR6; SG-delta; SGCDP; SGD

6444

Q92629

NM_000337

5q33.2-q33.3

E. coli

N-His

Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM), Viral myocarditis

Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM), Viral myocarditis

>50 ug/mL as determined by microplate BCA method

> 80% as determined by SDS-PAGE and Coomassie blue staining

Liquid

50mM Tris, 8M Urea, pH8.0.

Transmembrane

24.5 kDa

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

SGCD

Human

NP_000328

https://www.ncbi.nlm.nih.gov/gene/6444

https://www.uniprot.org/uniprot/Q92629

https://www.ncbi.nlm.nih.gov/nuccore/NM_000337

https://www.ncbi.nlm.nih.gov/nuccore/NP_000328