Demexiptiline

Demexiptiline is a tricyclic antidepressant. Demexiptiline is a norepinephrine reuptake inhibitor. Demexiptiline has a binding affinity with SARS-CoV-2 3CL protease of 8.14 kcal/mol. Demexiptiline can also be studied in research on melancholic states[1][2].

24701-51-7

12352005

SARS-CoV

Anti-infection

Neuroscience-Neuromodulation

Neurological Disease

CNCCO/N=C1C2=CC=CC=C2C=CC3=CC=CC=C/13

C18H18N2O

278.35

[1]Gao, K., et al., (2020) . Repositioning of 8565 Existing Drugs for COVID-19. The journal of physical chemistry letters, 11 (13), 5373-5382. |[2]Martin, A., et al., (1981) . La déméxiptiline dans le traitement des états mélancoliques (réflexions après trois années d'utilisation) [Demexiptiline in the treatment of melancholic states (reflections after 3 years of use) ]. Annales medico-psychologiques, 139 (9), 1023-1035.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-B2074/

Reference compound1

No Development Reported