Denosumab (TNFSF11/CD254) - Research Grid Biosimilar
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Denosumab is a novel, fully human IgG2 monoclonal antibody specific to receptor activator of nuclear factor kappa-B ligand (RANKL), suppresses bone resorption markers in patients with a variety of metastatic tumors and is being investigated in multiple clinical trials for the prevention and treatment of bone metastases. Chemically, it consists of 2 heavy and 2 light chains. Each light chain consists of 215 amino acids. Each heavy chain consists of 448 amino acids with 4 intramolecular disulfides. FDA approved on June 1, 2010.
Homo sapiens / TNFSF11/CD254 [Homo sapiens]
• Recombinant Monoclonal
Unconjugated
Primary Antibodies, Biosimilars
CHO cells
Neuroscience
>95%
Batch dependent
PBS buffer pH7.5
None
Blue Ice
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 ˚ C for 1-2 weeks. Store at -20 ˚ C for 12 months. Store at -80 ˚ C for long term storage.
IgG2-kappa
Homo sapiens
AMG162
Beschrijving
Denosumab (TNFSF11/CD254) - Research Grid Biosimilar Beschikbaar in 0.1 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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