Deoxy-thalidomide-C4-NH2
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Deoxy-thalidomide-C4-NH2 is a ligand-linker conjugate for the E3 ligase Cereblon (CRBN). Deoxy-thalidomide-C4-NH2 can be used in the synthesis of PROTAC BRD4 Degrader.
2940934-97-2
12352005
E3 Ligase Ligand-Linker Conjugates
PROTAC
Cancer
O=C1NC(C(CC1)N2C(C3=CC=C(CCCCN)C=C3C2)=O)=O
C17H21N3O3
315.37
[1]Lovato K, et al. Reductive C (sp2) -C (sp3) Coupling Protocol to Enable Linker Exploration of Cereblon E3-Ligase BRD4 Proteolysis-Targeting Chimeras. J Med Chem. 2025 May 22;68 (10) :10061-10074.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W957152/
Reference compound1
No Development Reported
Beschrijving
Deoxy-thalidomide-C4-NH2 is a ligand-linker conjugate for the E3 ligase Cereblon (CRBN). Deoxy-thalidomide-C4-NH2 can be used in the synthesis of PROTAC BRD4 De
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MS Solution sufficient for 400 Mini, 142 Midi, 33 Maxi
MS10
Each
MS pipette, variable vol µme 10~100 µL
MSP-100
1 Unit
MS 12-ch pipette, variable vol µme 20~200 µL
MSP-12X200
1 Unit
MS 12-ch pipette, variable vol µme 2~20 µL
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1 Unit
MS Rocking anti-moistured shaker with 30 x 30 cm platform and flat non-slip rubber mat
MS-NRK-3001
1 Unit
MS Orbital Shaker with 30 x 30 cm platform and flat non-slip rubber mat
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MS Reciprocal anti-moistured shaker with 30 x 30 cm platform and flat non-slip rubber mat
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MS pipette, variable vol µme 1000~10000 µL
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