[Des-Arg10]-HOE I40 (TFA)

[Des-Arg10]-HOE I40 TFA is a potent bradykinin B1 receptor antagonist[1].

12352209

Bradykinin Receptor

GPCR/G Protein

Metabolism-protein/nucleotide metabolism

Endocrinology; Inflammation/Immunology

99.84

N/C(N)=N\CCC[C@@H](C(N1CCC[C@H]1C(N2C[C@H](O)C[C@H]2C(NCC(N[C@H](C(N[C@@H](CO)C(N3CCC4=C(C=CC=C4)[C@@H]3C(N5[C@@]6([H])CCCC[C@]6(C[C@H]5C(O)=O)[H])=O)=O)=O)CC7=CC=CS7)=O)=O)=O)=O)NC([C@H](N)CCC/N=C(N)\N)=O.O=C(O)C(F)(F)F.[x]

C53H77N15O12S.xC2HF3O2

1148.34 (free base)

[1]Wirth KJ, et al. DesArg10[Hoe 140] is a potent B1 bradykinin antagonist. Agents Actions Suppl. 1992;38 (Pt 2) :406-13.

Blue Ice

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

http://file.medchemexpress.com/batch_PDF/HY-P5518A/Des-Arg10-HOE-I40-TFA-SDS-MedChemExpress.pdf

Peptides

No Development Reported

Bradykinin B1 Receptor (B1R)