Desmonomethylpromazine
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Desmonomethylpromazine is the brain-penetrant demethylated metabolite of Promazine. Desmonomethylpromazine can enter red blood cells and tissues through passive diffusion, distributes in tissues such as lung, liver, and kidney in rats[1][2].
2095-20-7
12352005
H315-H318-H335
Drug Metabolite
Metabolic Enzyme/Protease
Metabolic Disease
CNCCCN1C2=C(C=CC=C2)SC3=C1C=CC=C3
C16H18N2S
270.39
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362-P403+P233-P405-P501
[1]Daniel KRAPPMANN, et al. Selective inhibition of malt1 protease by phenothiazine derivatives. WO2013017637A1. 2013-02-07.|[2]Hu OY, et al. Stability, human blood distribution and rat tissue localization of promazine and desmonomethylpromazine. Biopharm Drug Dispos. 1989 Nov-Dec;10 (6) :537-48.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W641657/
Reference compound1
No Development Reported
Beschrijving
Desmonomethylpromazine is the brain-penetrant demethylated metabolite of Promazine. Desmonomethylpromazine can enter red blood cells and tissues through passive
Specificaties
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OneTaq Hot Start 2X Master Mix with GC Buffer
NEB M0485L
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