DGCR2 (NM 005137) Human Recombinant Proteïne

Deletions of the 22q11.2 have been associated with a wide range of developmental defects (notably DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome and isolated conotruncal cardiac defects) classified under the acronym CATCH 22. The DGCR2 gene encodes a novel putative adhesion receptor protein, which could play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]

Purified recombinant protein of Human Human DiGeorge syndrome critical region gene 2 (DGCR2), transcript variant 1, Trp49-Phe330, with N-terminal His tag, expressed in E. coli, 50ug

DGS-C; IDD; LAN; SEZ-12

9993

P98153, Q8IWC8

NM_005137

22q11.21

E. coli

N-His

>50 ug/mL as determined by microplate BCA method

> 80% as determined by SDS-PAGE and Coomassie blue staining

Liquid

50mM Tris, 8M Urea, pH8.0

Druggable Genome, Transmembrane

32.2 kDa

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

DGCR2

Human

NP_005128

https://www.ncbi.nlm.nih.gov/gene/9993

https://www.uniprot.org/uniprot/P98153

https://www.ncbi.nlm.nih.gov/nuccore/NM_005137

https://www.ncbi.nlm.nih.gov/nuccore/NP_005128