DHFR Antilichaam

Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia. Several transcript variants encoding different isoforms have been found for this gene.

1719

P00374

Human, Mouse

Recombinant fusion protein containing a sequence corresponding to amino acids 1-187 of human DHFR (NP_000782.1) .

Unconjugated

Primary Antibodies

Cancer, Cell Cycle, Signal Transduction

Affinity purification

HeLa

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 19kDa

IgG

DHFR

22Rv1

K-562

HL-60

THP-1

Raji

Dihydrofolate reductase

Homo sapiens

DHFRP1, DYR, dihydrofolate reductase

WB, IF

Liquid