DHFR Mouse Monoclonal Antibody [Kloon ID: LBI6G7]

Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia.

Carrier-free (BSA/glycerol-free) DHFR mouse monoclonal antibody, clone LBI6G7

DHFRP1; DYR

Homo sapiens dihydrofolate reductase (DHFR), transcript variant 1, mRNA.

1719

P00374

Unconjugated

Folate biosynthesis, Metabolic pathways, One carbon pool by folate

Folate biosynthesis, Metabolic pathways, One carbon pool by folate

WB 1:2000 IHC 1:50 IF 1:100

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Stem cell - Pluripotency

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

DHFR

https://www.ncbi.nlm.nih.gov/gene/?term=1719

https://www.uniprot.org/uniprot/P00374