DHH Antilichaam

This gene encodes a member of the hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development.

50846

O43323

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 199-396 of human DHH (NP_066382.1) .

Unconjugated

Primary Antibodies

Cell Cycle, Stem Cell

Affinity purification

Mouse skeletal muscle

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 44kDa

IgG

WB: 1:500 - 1:2000

DHH

Rat skeletal muscle

Desert hedgehog protein

Homo sapiens

Desert hedgehog protein, DHH, HHG-3, Desert hedgehog protein N-product, Desert hedgehog protein C-product, DHH

WB

Liquid