DHX36 Antilichaam

DHX36 Antibody: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure. DHX36 (DEAH box protein 36), also known as MLE-like protein 1 and RNA helicase associated with AU-rich element ARE (RHAU), belongs to RNA helicase of the DEAH family and may function in sex development and spermatogenesis. It is expressed in testis and is evolutionary conserved with true orthologs in almost all animal species. DHX36 plays a role in degradation and deadenylation of mRNAs containing in their 3'-UTR the consensus ARE sequence element. DHX36 is required for early embryogenesis.

170506

Q9H2U1

NP_065916

Human, Mouse

Unconjugated

Primary Antibodies

Stem Cell

DHX36 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1404 - Mouse Liver Tissue Lysate

1 mg/mL

DHX36 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

DHX36 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

Predicted: 111 kDa

IgG

At least four isoforms of DDX36 are known to exist; this antibody will detect the three longest isoforms.

DHX36

Cat. No. 10-201 - Human Liver Tissue Slide

DEAH (Asp-Glu-Ala-His) box polypeptide 36

Homo sapiens

Cordin O, Banroques J, Tanner NK, et al. The DEAD-box protein family of RNA helicases. Gene 2006; 367:17-37.

Linder P. Dead-box proteins: a family affair—active and passive players in RNP-remodeling. Nucleic Acids Res. 2006; 34:4168-80.

Lattmann S, Giri B, Vaughn JP, et al. Role of the amino terminal RHAU-specific motif in the recognition and resolution of guanine quadruplex-RNA by the DEAH-box RNA helicase RHAU. Nucleic Acids Res. 2010; 38:6219-33.

Fu JJ, Li LY, Liu SF, et al. Expression research for human DDX36 and mouse Ddx36 gene in the adult testis. Yi Chuan Xue Bao 2003; 30: 201-208.

DHX36 Antibody: G4R1, RHAU, DDX36, MLEL1, KIAA1488, Probable ATP-dependent RNA helicase DHX36, DEAH box protein 36

ELISA, WB, IHC-P

167830433

Liquid