
Diazaquinomycine A
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Diazaquinomycin A (DAQA), a diaza-anthracene antibiotic, is a thymidylate synthase inhibitor. Diazaquinomycin A (DAQA) induces DNA damage, cell cycle arrest, and apoptosis through cleaved-PARP[1].
87614-40-2
12352005
Apoptosis; Thymidylate Synthase
Apoptosis
Cancer
O=C1NC(C(C(N2)=C3C(CCC)=C(C)C2=O)=O)=C(C(CCC)=C1C)C3=O
C20H22N2O4
354.40
[1]Michael W Mullowney, et al. Diazaquinomycins E-G, novel diaza-anthracene analogs from a marine-derived Streptomyces sp. Mar Drugs. 2014 Jun 11;12 (6) :3574-86.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-N14161/
Natural Products
No Development Reported
Beschrijving
Diazaquinomycin A (DAQA), a diaza-anthracene antibiotic, is a thymidylate synthase inhibitor. Diazaquinomycin A (DAQA) induces DNA damage, cell cycle arrest, an
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