
Diclofenac Amide-13C6
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Diclofenac Amide-13C6 is the 13C-labeled Diclofenac amide. Diclofenac amide is a prodrug for Diclofenac sodium (HY-15037). Diclofenac amide is an orally active inhibitor for COX-1/2, that inhibits the production of prostaglandins (PG) and thromboxanes (TX). Diclofenac amide exhibits anti-inflammatory efficacy in Carrageenan (HY-125474) -induced rat paw edema model without causing gastric ulcer (300 μmol/kg).
12352005
COX; Isotope-Labeled Compounds
Immunology/Inflammation; Others
COVID-19-immunoregulation
Inflammation/Immunology
O=C1C[13C]2=[13C]([13C]([H])=[13C]([13C]([H])=[13C]2N1C3=C(C=CC=C3Cl)Cl)[H])[H]
C8 13C6H9Cl2NO
284.09
[1]Santos JL, et al., Pharmacological evaluation and preliminary pharmacokinetics studies of a new diclofenac prodrug without gastric ulceration effect. Int J Mol Sci. 2012 Nov 19;13 (11) :15305-20.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W747879/
Isotope-Labeled Compounds
No Development Reported
Beschrijving
Diclofenac Amide-13C6 is the 13C-labeled Diclofenac amide. Diclofenac amide is a prodrug for Diclofenac sodium (HY-15037). Diclofenac amide is an orally active
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