Diethyllfumaraat (standaard)

Diethyl fumarate (Standard) is the analytical standard of Diethyl fumarate. This product is intended for research and analytical applications. Diethyl fumarate is a decomposition product of Malathion 9 (a pesticide) and reactant in the Diels-Alder reaction. Diethyl fumarate is a reputed skin irritant. Diethyl fumarate can causes non-immunologic contact urticaria on skin. Diethyl fumarate and Curcumin (HY-N0005) hybridize to exert neuroprotective effects[1][2][3][4].

623-91-6

Others; Reference Standards

Others

Inflammation/Immunology; Neurological Disease

O=C(OCC)/C=C/C(OCC)=O

C8H12O4

172.18

[1]Jr FA, et, al. Gas chromatographic determination of diethyl fumarate in malathion extracts and preparations used for control of body lice. J Econ Entomol. 1968 Apr;61 (2) :457-9.|[2]Lahti A, et, al. Contact urticaria from diethyl fumarate. Contact Dermatitis. 1985 Mar;12 (3) :139-40.|[3]Di Martino RMC, et al. Novel Curcumin-Diethyl Fumarate Hybrid as a Dualistic GSK-3β Inhibitor/Nrf2 Inducer for the Treatment of Parkinson's Disease. ACS Chem Neurosci. 2020 Sep 2;11 (17) :2728-2740. |[4]Silvestri M G, et al. A kinetic study of the Diels-Alder reaction: An experiment illustrating simple second-order reaction kinetics. Journal of Chemical Education, 1989, 66 (8) : 690.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W010056R/

Reference Standards