Difenyltindichloride-d10
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Diphenyltin Dichloride-d10 is the deuterium labeled NSC405640. NSC405640 is a potent inhibitor of the MDM2-p53 interaction. NSC405640 rescues structural p53 mutations. NSC405640 selectively inhibits the growth of cell lines with wild-type p53[1].
12352005
Isotope-Labeled Compounds; MDM-2/p53
Apoptosis; Others
Cancer
Cl[Sn](Cl)(C1=C(C([2H])=C(C([2H])=C1[2H])[2H])[2H])C2=C(C([2H])=C(C([2H])=C2[2H])[2H])[2H]
C12D10Cl2Sn
353.89
[1]Chen S, et al. Arsenic Trioxide Rescues Structural p53 Mutations through a Cryptic Allosteric Site. Cancer Cell. 2021;39 (2) :225-239.e8.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W704348/
Isotope-Labeled Compounds
No Development Reported
Beschrijving
Diphenyltin Dichloride-d10 is the deuterium labeled NSC405640. NSC405640 is a potent inhibitor of the MDM2-p53 interaction. NSC405640 rescues structural p53 mut
Specificaties
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