Difosfomevalonaat decarboxylase Antilichaam / MVD

The enzyme mevalonate pyrophosphate decarboxylase (MVD; EC 4.1.1.33) catalyzes the conversion of mevalonate pyrophosphate into isopentenyl pyrophosphate. This unusual enzyme decarboxylates and dehydrates its substrate while hydrolyzing ATP. As a unique enzyme in one of the early steps in cholesterol biosynthesis, MVD may be a useful target for drugs aimed at lowering serum cholesterol levels. This gene is mapped to chromosome 16q24.3 based on an alignment of the MVD sequence.

Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Flow cytometry: 1-3ug/million cells, ELISA: 0.1-0.5 µg/mL

P53602

Human, Mouse

An E.coli-derived human recombinant protein (amino acids E62-Q374) was used as the immunogen for the Diphosphomevalonate decarboxylase antibody.

WB, IHC-P, FACS, ELISA

Antigen affinity purified

Antigen affinity purified

Lyophilized from 1X PBS with 2% Trehalose

This Diphosphomevalonate decarboxylase antibody is available for research use only.

After reconstitution, the Diphosphomevalonate decarboxylase antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Optimal dilution of the Diphosphomevalonate decarboxylase antibody should be determined by the researcher.

Cytoplasm

IHC staining of FFPE mouse ovary tissue with Diphosphomevalonate decarboxylase antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.