Dihydrochlamydocin-analogen 1
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Dihydrochlamydocin analog-1 (compound 2) is a Chlamydocin analogue that inhibits histone H4 peptide deacetylation with IC50 of 30 nM[1].
157618-75-2
12352209
H302+H312+H332
HDAC
Cell Cycle/DNA Damage; Epigenetics
Cancer-programmed cell death
Cancer
O=C1N2[C@@](CCC2)([H])C(N[C@H](C(NC(C)(C(N[C@H]1CC3=CC=CC=C3)=O)C)=O)CCCCCC([C@H](O)C)=O)=O
C28H40N4O6
528.64
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501
[1]Simone Di Micco, et al. Molecular modeling studies toward the structural optimization of new cyclopeptide-based HDAC inhibitors modeled on the natural product FR235222. Bioorg Med Chem. 2008 Sep 15;16 (18) :8635-42.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-P2178/
Peptides
No Development Reported
Beschrijving
Dihydrochlamydocin analog-1 (compound 2) is a Chlamydocin analogue that inhibits histone H4 peptide deacetylation with IC50 of 30 nM[1].
Specificaties
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