Dihydrouracil-13C,15N2
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Dihydrouracil-13C,15N2 (5,6-Dihydrouracil-13C,15N2) is the 13C- and 15N-labeled Dihydrouracil. Dihydrouracil (5,6-Dihydrouracil), a metabolite of Uracil, can be used as a marker for identification of dihydropyrimidine dehydrogenase (DPD) -deficient[1][2].
181516-96-1
5,6-Dihydrouracil-13C,15N2
12352005
Endogenous Metabolite; Isotope-Labeled Compounds
Metabolic Enzyme/Protease; Others
Metabolic Disease
O=C([15NH][13C]1=O)CC[15N]1[H]
C3 13CH6 15N2O2
117.08
[1]Henricks LM, et, al. Food-effect study on uracil and dihydrouracil plasma levels as marker for dihydropyrimidine dehydrogenase activity in human volunteers. Br J Clin Pharmacol. 2018 Dec;84 (12) :2761-2769.|[2]Jacobs BAW, et, al. The impact of liver resection on the dihydrouracil:uracil plasma ratio in patients with colorectal liver metastases. Eur J Clin Pharmacol. 2018 Jun;74 (6) :737-744.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W779020/
Isotope-Labeled Compounds
No Development Reported
Beschrijving
Dihydrouracil-13C,15N2 (5,6-Dihydrouracil-13C,15N2) is the 13C- and 15N-labeled Dihydrouracil. Dihydrouracil (5,6-Dihydrouracil), a metabolite of Uracil, can be
Specificaties
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