Dimethyldiacetylcystinaat
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Dimethyl diacetyl cystinate (DACDM) is a potent NF-κB inhibitor. Dimethyl diacetyl cystinate shifts the intracellular redox balance toward the oxidized state by increasing intracellular oxidized glutathione (GSSG) content, competitively blocking the binding of activated NF-κB to DNA, thereby inhibiting the production of inflammatory factors such as IL-1κ. Dimethyl diacetyl cystinate is promising for research of UVB-induced skin inflammation and related oxidative stress diseases[1].
32381-28-5
DACDM
12352211
H302-H315-H319
Interleukin Related; NF-κB
Immunology/Inflammation; NF-κB
Metabolic Disease; Inflammation/Immunology
CC(N[C@H](C(OC)=O)CSSC[C@H](NC(C)=O)C(OC)=O)=O
C12H20N2O6S2
352.43
P264-P270-P280-P302+P352-P330-P362+P364-P501
[1]Kitazawa M, et al. Intracellular redox regulation by a cystine derivative suppresses UV-induced NF-kappa B activation. FEBS Lett. 2002 Aug 28;526 (1-3) :106-10.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W550315/
Reference compound1
No Development Reported
Beschrijving
Dimethyl diacetyl cystinate (DACDM) is a potent NF-κB inhibitor. Dimethyl diacetyl cystinate shifts the intracellular redox balance toward the oxidized state by
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