Diptericine

Diptericin is an antibacterial peptide, originally isolated from Phormia terranovae. Diptericin exhibits potent and selective activity against specific Gram-negative bacteria, such as Escherichia coli and Salmonella typhimurium. Diptericin kills bacteria within 1 hour. Diptericin can be used for antibacterial research[1].

12352209

Bacterial

Anti-infection

Infection

O=C(N[C@@H](CC(C)C)C(N[C@@H](CC1=CNC=N1)C(N[C@@H]([C@@H](C)CC)C(N2[C@@H](CCC2)C(N3[C@@H](CCC3)C(N4[C@@H](CCC4)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(N)=O)C(N[C@@H](CCCCN)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(N)=O)C(N[C@@H](CC5=CNC6=CC=CC=C56)C(N7[C@@H](CCC7)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(NCC(NCC(NCC(NCC(NCC(N[C@@H](CO)C(N8[C@@H](CCC8)C(N[C@@H](CCCCN)C(N[C@@H]([C@H](O)C)C(NCC(N[C@@H](CC9=CC=C(C=C9)O)C(N[C@@H](CC(O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(N)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(N)=O)C(N[C@@H](C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCCN)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC(O)=O)N

C173H268N50O55

3928.28

[1]Cudic M, et al. Chemical synthesis, antibacterial activity and conformation of diptericin, an 82-mer peptide originally isolated from insects. Eur J Biochem. 1999 Dec;266 (2) :549-58.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-P11168/

Peptides

No Development Reported