Dipyrithione (standaard)

Dipyrithione (Standard) is the analytical standard of Dipyrithione. This product is intended for research and analytical applications. Dipyrithione is a potent antimicrobial agent. Dipyrithione shows antifungal activity and antiproliferative activity. Dipyrithione induces apoptosis and cycle arrest at G1 phase. Dipyrithione shows anti-inflammatory activity in vivo. Dipyrithione shows anti-tumor activity. Dipyrithione has the potential for the research of dermatophytosis[1][2][3].

3696-28-4

Apoptosis; Bacterial; Fungal; Reference Standards

Anti-infection; Apoptosis; Others

Cancer; Infection; Inflammation/Immunology

[O-][N+]1=CC=CC=C1SSC2=CC=CC=[N+]2[O-]

C10H8N2O2S2

252.31

[1]Song X, et al. In vivo antifungal activity of dipyrithione against Trichophyton rubrum on guinea pig dermatophytosis models. Biomed Pharmacother. 2018 Dec;108:558-564.|[2]Liu Z, et al. Dipyrithione inhibits lipopolysaccharide-induced iNOS and COX-2 up-regulation in macrophages and protects against endotoxic shock in mice. FEBS Lett. 2008 May 28;582 (12) :1643-50.|[3]Fan Y, et al. Dipyrithione induces cell-cycle arrest and apoptosis in four cancer cell lines in vitro and inhibits tumor growth in a mouse model. BMC Pharmacol Toxicol. 2013 Oct 21;14:54.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-N8432R/

Reference Standards