DIS3L Polyklonale Antilichaam, AbBy FluorTM 488 Vervoeging
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
The exosome is a multi-protein complex composed of several highly conserved subunits, some of which are 3? to 5? exoribonucleases. The complex is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich elements (AREs) in their untranslated 3? regions. DIS3, also known as RRP44, is a 958 amino acid protein that localizes to both the cytoplasm and the nucleus and contains one PINc domain. Widely expressed with highest expression in testis, DIS3 functions as a component of the exosome exoribonuclease complex and is required for processing of 7S pre-RNA into a mature nuclear complex and, ultimately, for proper mitotic progression. Abnormal expression levels of DIS3 may be associated with colon cancer, suggesting a role for DIS3 in tumorigenesis. Multiple isoforms of DIS3 exist due to alternative splicing events.
DIS3 like exonuclease 1; DIS3 mitotic control homolog S. cerevisiae like; FLJ38088; KIAA1955; MGC4562; DI3L1_HUMAN.
115752
• Rabbit
Human, Mouse, Rat
701-800/1054
DIS3L
• Polyclonal
• IgG
AbBy Fluor™ 488
KLH conjugated synthetic peptide derived from human DIS3L
WB, IF (IHC-P)
Purified by Protein A.
499nm/519nm
1µg/µl
WB (1:300-5000), IF (IHC-P) (1:50-200)
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Unmodified
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
115752
Beschrijving
DIS3L Polyklonale Antilichaam, AbBy FluorTM 488 Vervoeging Beschikbaar in 100 µL. Bestel eenvoudig online met snelle levering.
Specificaties
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