Disorazol A
Gecertificeerd

Disorazol A

Catalog #: TN10381-01
Maat: 10 mg

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%
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BTW niet inbegrepen
Gratis verzending vanaf €100
Technische Documentatie

Technische Specificaties

CAS Number

158181-47-6

Target

Apoptosis, Antifungal, Microtubule Associated

Related Pathways

Cytoskeletal Signaling, Apoptosis, Microbiology/Virology

Bioactivity

Disorazol A1 is a tubulin inhibitor with antifungal properties. It functions by inhibiting tubulin polymerization and disrupting microtubule formation, thereby blocking mitosis and arresting the cell cycle at the G2/M phase, which induces apoptosis. Disorazol A1 also inhibits L929 mouse fibroblasts with an IC50 value of 3 pm and causes accumulation of p53 protein in the nucleus. Disorazol A1 holds potential for cancer research.

Smiles

C/C=C/[C@@H](C(C)(C)[C@@H]1C/C=C\C=C/C=C\[C@@H](CC2=NC(=CO2)C(=O)O[C@@H](C/C=C\[C@@H]3[C@@H](O3)/C=C\C=C/C4=NC(=CO4)C(=O)O1)C(C)(C)[C@H](/C=C/C)O)OC)O

Molecular Formula

C43H54N2O10

Molecular Weight

758.896

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Beschrijving

Disorazol A Beschikbaar in 10 mg. Bestel eenvoudig online met snelle levering.

Specificaties

ProductnaamDisorazol A
Categorie
Beschikbare grootte10 mg
CatalogusnummerTN10381-01