DLAT Antilichaam - C-terminaal gebied: Biotine (ARP41995 P050-Biotine)

Dihydrolipoamide S-acetyltransferase

E2, PBC, DLTA, PDCE2, PDC-E2

1737

Q86YI5

NP_001922

Human, Mouse, Rat, Dog, Pig, Zebrafish

The immunogen is a synthetic peptide directed towards the C terminal region of human DLAT

DLAT is dihydrolipoamide acetyltransferase, the E2 subunit of the mammalian pyruvate dehydrogenase complex of the inner mitochondrial membrane. Patients with primary biliary cirrhosis show autoantibodies to DLAT.The DLAT gene encodes dihydrolipoamide acetyltransferase (EC 2.3.1.12), the E2 subunit of the mammalian pyruvate dehydrogenase complex (PDC; EC 1.2.4.1) of the inner mitochondrial membrane. Patients with primary biliary cirrhosis (PBC; MIM 109720) show autoantibodies to DLAT.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-2696 AK057299.1 1-2696 2697-3933 BC039084.1 2066-3302 3934-4322 DB551427.1 98-486

MDM2; UBC; ADRB2; PRKD3; PDHX; MMGT1; MRPL1; ACAD9; SYNCRIP; PDHA2; PDHA1; OGDH; NDUFS4; HSPA1L; DLD; COX5B; COPS5; CUL1; SIRT7; TSG101; KIAA0101; PSMA3; PDK4; PDK3; PDK2; PDK1; PDHB

Biotin

Polyclonal Antibody

WB

Affinity Purified

DLAT is strongly supported by BioGPS gene expression data to be expressed in HepG2

0.5 mg/ml

Dog: 100%; Human: 100%; Mouse: 100%; Pig: 92%; Rat: 100%; Zebrafish: 92%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

69kDa

Korotchkina, L.G. (2008) FEBS Lett. 582 (3), 468-472

Wet Ice

647

DLAT

DLAT

Rabbit

Dihydrolipoamide S-acetyltransferase EMBL AAH39084.1

NM_001931

DVVSLATKAREGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQACILA