DLC1 Antilichaam - C-terminaal gebied: Biotine (ARP52138_P050-Biotine)

Deleted in liver cancer 1

HP, ARHGAP7, STARD12, p122-RhoGAP

10395

Q9Y238

EAW63852

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the C terminal region of human DLC1

This gene is deleted in the primary tumor of hepatocellular carcinoma. It maps to 8p22-p21.3, a region frequently deleted in solid tumors. It is suggested that this gene is a candidate tumor suppressor gene for human liver cancer, as well as for prostate, lung, colorectal, and breast cancers. DLC1 functions as a GTPase-activating protein specific for Rho and an activator of PLCD1 in vivo and induces morphological changes and detachment through cytoskeletal reorganization.

DDB1; FBXW5; CUL1; CUL2; CUL3; CUL4A; UBC; TENC1; CAV1; S100A10; WWC1; AKT1

Biotin

Polyclonal Antibody

WB

Affinity Purified

There is BioGPS gene expression data showing that DLC1 is expressed in 721_B

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 79%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

52kDa

Wet Ice

467

DLC1

DLC1

Rabbit

Deleted in lung and esophageal cancer protein 1

NM_001164271

NLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGL