DLD Antilichaam

This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In homodimeric form, the encoded protein functions as a dehydrogenase and is found in several multi-enzyme complexes that regulate energy metabolism. However, as a monomer, this protein can function as a protease. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency. Alternative splicing results in multiple transcript variants.

1738

P09622

Human, Mouse

Recombinant fusion protein containing a sequence corresponding to amino acids 36-300 of human DLD (NP_000099.2) .

Unconjugated

Primary Antibodies

Cancer, Signal Transduction

Affinity purification

MCF7

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 54kDa

IgG

DLD

BT-474

K-562

293T

Mouse liver

Dihydrolipoamide dehydrogenase

Homo sapiens

DLD, DLDH, E3, GCSL, LAD, PHE3, DLDD

WB, IHC, IF

Liquid