DMD Antilichaam

This gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene.

1756

P11532

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 346-635 of human DMD (NP_004007.1) .

Unconjugated

Primary Antibodies

Cell Cycle, Neuroscience, Signal Transduction, Stem Cell

Affinity purification

Mouse heart

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 427kDa

IgG

DMD

Dystrophin

Homo sapiens

BMD, CMD3B, DXS142, DXS164, DXS206, DXS23DXS239, DXS268, DXS269, DXS27DXS272, MRX85, dystrophin

WB, IHC, IF

Liquid