dmDNA31

DmDNA31 is a rifamycin-class antibiotic that inhibits bacterial DNA-dependent RNA polymerase with potent bactericidal activity against S. aureus[1].

845625-44-7

12352005

Antibiotic; Bacterial

Reference compound

Anti-infection

COVID-19-anti-virus

Infection

https://www.medchemexpress.com/dmdna31.html

98.64

DMSO : 25 mg/mL (ultrasonic)

O=C1C2=C(O[C@@]1(O/C=C\[C@]([C@H]([C@H]([C@@H]([C@@H]([C@@H]([C@@H](O)[C@@H](C)/C=C/C=C(C)/C3=O)C)O)C)OC(C)=O)C)([H])OC)C)C(C)=C(O)C4=C2C(C(OC5=CC(N6CCC(N(C)C)CC6)=C7)=C(N3)C4=O)=NC5=C7O

C50H62N4O13

927.05

[1]Peck M, et al. A Phase 1, Randomized, Single-Ascending-Dose Study To Investigate the Safety, Tolerability, and Pharmacokinetics of DSTA4637S, an Anti-Staphylococcus aureus Thiomab Antibody-Antibiotic Conjugate, in Healthy Volunteers. Antimicrob Agents Chemother. 2019 May 24;63 (6) .

Room Temperature

-20°C, 3 years; 4°C, 2 years (Powder)

http://file.medchemexpress.com/batch_PDF/HY-128916/dmDNA31-SDS-MedChemExpress.pdf

Reference compound1

No Development Reported