DMP-851
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
DMP-851 is a cyclic urea HIV protease inhibitor, with a Ki of 0.021 nM. DMP-851 shows antiviral activity against laboratory strains of HIV-l and HIV-2 as well as against primary clinical isolates derived from Zidovudine -resistant samples (A018C, E, WR 10983).
188978-02-1
12352005
HIV; HIV Protease
Anti-infection; Metabolic Enzyme/Protease
Infection
O=C1N(CC2=CC3=C(NN=C3N)C=C2)[C@H](CC4=CC=CC=C4)[C@H](O)[C@@H](O)[C@@H](CC5=CC=CC=C5)N1CCCC
C31H37N5O3
527.66
[1]Rodgers JD, et al. Design and selection of DMP 850 and DMP 851: the next generation of cyclic urea HIV protease inhibitors. Chem Biol. 1998 Nov;5 (11) :R312.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-19281/
Reference compound1
Phase 1
HIV-1; HIV-2
Beschrijving
DMP-851 is a cyclic urea HIV protease inhibitor, with a Ki of 0.021 nM. DMP-851 shows antiviral activity against laboratory strains of HIV-l and HIV-2 as well a
Specificaties
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