DNA Polymerase beta Polyklonale Antilichaam, APC-Cy7 Vervoeging

Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

DNA polymerase beta; POLB

5423

P06746

Nucleus

55-160/335

DNA Polymerase beta

APC-Cy7

KLH conjugated synthetic peptide derived from human DNA Polymerase beta

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purified by Protein A.

650nm/780nm

1µg/µl

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

5423

Human, Mouse, Rat, Dog, Cow, Pig, Horse, Chicken