DNAJA4 Antilichaam

The DNAJA4 protein is the mammalian homolog of the chaperone HSP40 (1) and acts as a co-chaperone with the heat shock protein HSP70 (2) . DNAJA4 is highly expressed in heart and testis, accounting for approximately 1% of total protein in mouse heart (2) . DNAJA4 is also regulated by the sterol regulatory element binding transcription factor 2 (SREBF2) and plays a role in the synthesis of cholesterol (3) .

55466

Q8WW22

NP_061072

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Homeostasis

DNAJA4 antibody is affinity chromatography purified via peptide column.

Cat. No. 1320 - Human Colon Tissue Lysate

1 mg/mL

Predicted species reactivity based on immunogen sequence: Bovine: (87%)

DNAJA4 antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

DNAJA4 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

IgG

DNAJA4 antibody is human, mouse, and rat reactive. At least three isoforms of DNAJA4 are known to exist; this antibody will detect all three isoforms.

DNAJA4

DnaJ homolog subfamily A member 4

Homo sapiens

Ohtsuka K and Hata M. Mammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for their classification and nomenclature. Cell Stress Chaperones 2000; 5:98-112.

Abdul KM, Terada K, Gotoh T, et al. Characterization and functional analysis of a heart-enriched DnaJ / Hsp40 homolog dj4/DjA4. Cell Stress Chaperones 2002; 7:156-66.

Robichon C, Varret M, Le Liepvre X, et al. DnajA4 is a SREBP-regulated chaperone involved in the cholesterol biosynthesis pathway. Biochim. Biophys. Acta 2006; 1761:1107-13.

DnaJ homolog subfamily A member 4, MST104, MSTP104, PRO1472

ELISA, WB

194328758

Liquid