DNAJB4 Antilichaam

The protein encoded by this gene is a molecular chaperone, tumor suppressor, and member of the heat shock protein-40 family. The encoded protein binds the cell adhesion protein E-cadherin and targets it to the plasma membrane. This protein also binds incorrectly folded E-cadherin and targets it for endoplasmic reticulum-associated degradation. This gene is a strong tumor suppressor for colorectal carcinoma, and downregulation of it may serve as a good biomarker for predicting patient outcomes. Several transcript variants encoding different isoforms have been found for this gene.

11080

Q9UDY4

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 50-160 of human DNAJB4 (NP_008965.2) .

Unconjugated

Primary Antibodies

Cancer, Signal Transduction

Affinity purification

HeLa

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 38kDa

IgG

WB: 1:500 - 1:2000

DNAJB4

Mouse brain

Rat brain

DnaJ homolog subfamily B member 4

Homo sapiens

DnaJ homolog subfamily B member 4, Heat shock 40 kDa protein 1 homolog, HSP40 homolog, Heat shock protein 40 homolog, Human liver DnaJ-like protein, DNAJB4, DNAJW, HLJ1

WB

Liquid