DNM2 Antilichaam

Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined.

1785

P50570

Human, Mouse, Rat

A synthetic peptide of human DNM2

Unconjugated

Primary Antibodies

Apoptosis, Cell Cycle, Neuroscience, Signal Transduction

Affinity purification

BT-474

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 110kDa

IgG

DNM2

MCF7

SKOV3

Mouse testis

Mouse heart

Rat brain

Dynamin-2

Homo sapiens

Dynamin-2, 3.6.5.5, DNM2, DYN2

WB, IHC

Liquid