Dnp-RPLALWRS (TFA)

Dnp-RPLALWRS TFA is a fluorescent peptide substrate designed for human matrilysin (MMP-7) . After enzymatic cleavage of Dnp-RPLALWRS TFA at the alanine-leucine bond, the release of the Dnp group alleviates fluorescence quenching, thereby enabling real-time quantitative analysis of MMP-7 activity by increasing tryptophan emission. Dnp-RPLALWRS TFA provides a sensitive and efficient detection method for kinetic studies and inhibitor screenin[1].

12352209

Fluorescent Dye

Others

Others

99.04

OC[C@@H](C(O)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CC1=CNC2=C1C=CC=C2)NC([C@H](CC(C)C)NC([C@H](C)NC([C@H](CC(C)C)NC([C@H]3N(C([C@H](CCCNC(N)=N)NC4=CC=C([N+]([O-])=O)C=C4[N+]([O-])=O)=O)CCC3)=O)=O)=O)=O)=O)=O.FC(C(O)=O)(F)F

C54H78F3N17O16

1278.30

[1]Welch AR, et al. Purification of human matrilysin produced in Escherichia coli and characterization using a new optimized fluorogenic peptide substrate. Arch Biochem Biophys. 1995 Dec 1;324 (1) :59-64.

Blue Ice

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

http://file.medchemexpress.com/batch_PDF/HY-P3123A/Dnp-RPLALWRS-TFA-SDS-MedChemExpress.pdf

Peptides

No Development Reported