DOC4 Antilichaam

This gene is a member of the dedicator of cytokinesis (DOCK) family and encodes a protein with a DHR-1 (CZH-1) domain, a DHR-2 (CZH-2) domain and an SH3 domain. This membrane-associated, cytoplasmic protein functions as a guanine nucleotide exchange factor and is involved in regulation of adherens junctions between cells. Mutations in this gene have been associated with ovarian, prostate, glioma, and colorectal cancers. Alternatively spliced variants which encode different protein isoforms have been described, but only one has been fully characterized.

9732

Q8N1I0

Human

Recombinant fusion protein containing a sequence corresponding to amino acids 150-450 of human DOCK4 (NP_055520.3) .

Unconjugated

Primary Antibodies

Signal Transduction

Affinity purification

DU145

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 235kDa

IgG

WB: 1:500 - 1:2000

DOCK4

Dedicator of cytokinesis 4

Homo sapiens

Dedicator of cytokinesis protein 4

WB

Liquid