DOCK2 Mouse Monoclonal Antibody [Kloon ID: UMLBI142]

The protein encoded by this gene belongs to the CDM protein family. It is specifically expressed in hematopoietic cells, predominantly in the peripheral blood leukocytes, and is involved in remodeling of the actin cytoskeleton required for lymphocyte migration, through the activation of RAC. Mice lacking this gene show a severe impairment in the migration and homing of lymphocytes. These mutant mice also exhibited long-term survival of allografts, suggesting that this gene may be a target for controlling transplant rejection. [provided by RefSeq, Oct 2011]

Carrier-free (BSA/glycerol-free) DOCK2 mouse monoclonal antibody, clone UMLBI142

FLJ46592; KIAA0209

Homo sapiens dedicator of cytokinesis 2 (DOCK2), transcript variant 1, mRNA.

1794

Q92608

Unconjugated

Chemokine signaling pathway, Fc gamma R-mediated phagocytosis

Chemokine signaling pathway, Fc gamma R-mediated phagocytosis

WB 1:2000, IHC 1:150

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

DOCK2

https://www.ncbi.nlm.nih.gov/gene/?term=1794

https://www.uniprot.org/uniprot/Q92608