Docosaanzuur-13C4

Docosanoic acid-13C4 (Behenic acid-13C4) is the 13C-labeled Docosanoic acid. Docosanoic acid (Behenic acid) is a long-chain saturated fatty acid. Docosanoic acid inhibits the double-stranded DNA (dsDNA) binding activity of p53 DNA binding domain, with a Kd of 12 nM. Docosanoic acid has low bioavailability and can increase cholesterol in vivo[1][2][3].

2785462-39-5

Behenic acid-13C4

12352211

DNA/RNA Synthesis; Endogenous Metabolite; Isotope-Labeled Compounds

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Others

Metabolic Disease

CCCCCCCCCCCCCCCCCC[13CH2][13CH2][13CH2][13C](O)=O

C18 13C4H44O2

344.55

[1]Cater NB, et al. Behenic acid is a cholesterol-raising saturated fatty acid in humans. Am J Clin Nutr. 2001 Jan;73 (1) :41-4.|[2]Moreira DK, et al. Evaluation of structured lipids with behenic acid in the prevention of obesity. Food Res Int. 2017 May;95:52-58. |[3]Iijima H, et al. The inhibitory action of long-chain fatty acids on the DNA binding activity of p53. Lipids. 2006 Jun;41 (6) :521-7.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W013049S6/

Isotope-Labeled Compounds

No Development Reported