Docosaanzuur (standaard)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Docosanoic acid (Behenic acid) is a long-chain saturated fatty acid. Docosanoic acid inhibits the double-stranded DNA (dsDNA) binding activity of p53 DNA binding domain, with a Kd of 12 nM. Docosanoic acid has low bioavailability and can increase cholesterol in humans[1][2][3].
112-85-6
12352211
H302-H315-H319-H335
DNA/RNA Synthesis; Endogenous Metabolite
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Cancer; Metabolic Disease
CCCCCCCCCCCCCCCCCCCCCC(O)=O
C22H44O2
340.59
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
[1]Cater NB, et al. Behenic acid is a cholesterol-raising saturated fatty acid in humans. Am J Clin Nutr. 2001 Jan;73 (1) :41-4.|[2]Moreira DK, et al. Evaluation of structured lipids with behenic acid in the prevention of obesity. Food Res Int. 2017 May;95:52-58. |[3]Iijima H, et al. The inhibitory action of long-chain fatty acids on the DNA binding activity of p53. Lipids. 2006 Jun;41 (6) :521-7.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W013049R/
Reference Standards
No Development Reported
Human Endogenous Metabolite
Beschrijving
Docosanoic acid (Behenic acid) is a long-chain saturated fatty acid. Docosanoic acid inhibits the double-stranded DNA (dsDNA) binding activity of p53 DNA bindin
Specificaties
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