Dopamine b-Hydroxylase Antilichaam

Dopamine beta-hydroxylase (DBH) catalyzes the conversion of dopamine to norepinephrine and serves as a marker of noradrenergic cells. The expression of DBH is elevated during stress.

1621

P09172

P09172

Human, Rat, Sheep, Bovine

DBH polyclonal antibody was raised against a synthetic peptide from the N-terminal region of human DBH, conjugated to keyhole limpet hemocyanin.

Unconjugated

Primary Antibodies

Neuroscience

Affinity Purified

Batch dependent

None

Blue Ice

For long term storage –80˚ C is recommended, but shorter term storage at –20˚ C is also acceptable as aliquots may be taken without freeze/thawing due to the presence of 50% glycerol. Stable for one year.

75

Dopamine b-Hydroxylase, NT antibody is specific immunolabeling of the ~75k DBH protein in Western blots of human adrenal medulla.

Applications include Dot Blots (DB) and Western Blots (WB) . Sheep anti-DBH recognizes DBH in bovine, human, monkey and rat tissues. When internally tested under ideal conditions the working dilutions were 1:1000 for DB and WB.

DBH

Dopamine beta-hydroxylase (dopamine beta-monooxygenase)

Homo sapiens

Sabban, E.L., Kvetnansky, R. "Stress-triggered activation of gene expression in catecholaminergic systems: dynamics of transcriptional events, " Trends Neurosci. 24 (2001) 91 - 98.

Nagatsu, I, Kobayashi, K, Fujii, T, Komori, K, Sekiguchi, K, Titani, K, Fujita, K, and Nagatsu, T. "Antibodies raised against different oligopeptide segments of human dopamine-β -hydroxylase, " Neuroscience Letters, 120 (1990) 141 - 145.

WB

158517849

Liquid