Dopamine D2-receptorantagonist-3
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Dopamine D2 receptor antagonist-3 (Example 17) is an orally active and selective dopamine D2 receptor antagonist with a pIC50 of 5.52. Dopamine D2 receptor antagonist-3 exhibits antipsychotic activity in the Apomorphine induced agitation in rats. Dopamine D2 receptor antagonist-3 can be used for psychiatric and neurological disorders research[1].
1032714-06-9
12352005
Dopamine Receptor
GPCR/G Protein; Neuronal Signaling
Neuroscience-Neuromodulation
Neurological Disease
FC1=CC(CN2CCC(NC3=NN=C(C#N)C=C3)CC2)=CC(C(F)(F)F)=C1
C18H17F4N5
379.35
[1]Gregor James MacDonal, et al. Piperidinylamino-pyridazines and their use as fast dissociating dopamine 2 receptor antagonists. US8466153. 2013-06-18.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W648166/
Reference compound1
No Development Reported
D2 Receptor
Beschrijving
Dopamine D2 receptor antagonist-3 (Example 17) is an orally active and selective dopamine D2 receptor antagonist with a pIC50 of 5.52. Dopamine D2 receptor anta
Specificaties
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