Dopamine Decarboxylase Antilichaam

Aromatic L-amino acid decarboxylase (AADC; DOPA decarboxylase; DDC) catalyzes the second reaction in the biosynthesis of catecholamines and serotonin. It is also involved in the biosynthesis of trace amines.

280762

P27718

P27718

Rat, Bovine

DOPA Decarboxylase polyclonal antibody was raised against a SDS denatured, recombinant bovine aromatic DDC expressed in E. coli and purified from inclusion bodies.

Unconjugated

Primary Antibodies

Neuroscience

Affinity Purified

Batch dependent

None

Blue Ice

For long term storage –80˚ C is recommended, but shorter term storage at –20˚ C is also acceptable as aliquots may be taken without freeze/thawing due to the presence of 50% glycerol. Stable for one year.

55

Dopamine Decarboxylase antibody is specific immunolabeling of the ~55k DDC protein in Western blots of rat adrenal medulla.

Applications include Dot Blots (DB) and Western Blots (WB) . Recognizes DDC in rat adrenal medulla and caudate. When internally tested under ideal conditions the working dilutions were 1:1000 for DB and WB.

DDC

Dopa decarboxylase (aromatic L-amino acid decarboxylase)

Bos taurus

Haycock, J.W., Becker, L., Ang, L., Furukawa, Y., Hornykiewicz, O., and Kish, S.J., "Marked disparity between age-related changes in dopamine and other presynaptic dopaminergic markers in human striatum, " J. Neurochem. 87 (2003) 574 - 585.

Waymire, J.C. and Haycock, J.W. "Lack of regulation of aromatic L-amino acid decarboxylase in intact bovine chromaffin cells, " J. Neurochem. 81 (2002) 589 - 593.

Berry, M.D., Juorio, A.V., Li, X.M., and Boulton, A.A. "Aromatic L-amino acid decarboxylase: a neglected and misunderstood enzyme, " Neurochem. Res. 21 (1996) 1075 -1087.

WB

125987819

Liquid