Doramapimod (BIRB 796)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
285983-48-4
C07901-5mg
P38 MAPK
MAPK
CC1=CC=C (C=C1) N2C (=CC (=N2) C (C) (C) C) NC (=O) NC3=CC=C (C4=CC=CC=C43) OCCN5CCOCC5
C31H37N5O3
Doramapimod (BIRB 796) is a pan-p38 MAPK inhibitor with IC50 of 38 nM, 65 nM, 200 nM and 520 nM for p38α/β/γ/δ in cell-free assays, and binds p38α with Kd of 0.1 nM in THP-1 cells, 330-fold greater selectivity versus JNK2, weak inhibition for c-RAF, Fyn and Lck, insignificant inhibition of ERK-1, SYK, IKK2.
2 years -80 in solvent
Beschrijving
Doramapimod (BIRB 796) Beschikbaar in 5 mg. Wordt geleverd met droogijs. Bestel eenvoudig online met snelle levering.
Specificaties
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