DOTA-BP1

DOTA-BP1 is a DOTA-modified BP1 (BCMA-targeting peptide) . DOTA-BP1 can be radiolabeled with [68Ga]Ga to produce a BCMA-targeting PET tracer. DOTA-BP1 can be used in the research of detecting BCMA in multiple myeloma[1].

12352209

Radionuclide-Drug Conjugates (RDCs)

Antibody-drug Conjugate/ADC Related

Cancer

O=C([C@@H](NC(CN1CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1)=O)CCC(O)=O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CS)=O)CC2=CC=CC=C2)=O)CC(O)=O)=O)CC3=CC=C(O)C=C3)=O)CC4=CC=CC=C4)=O)CS)=O)CC5=CC=C(O)C=C5)=O)CCC(O)=O

C72H93N13O25S2

1604.71

[1]Song L, et al. Development of a Novel Peptide-Based PET Tracer [68Ga]Ga-DOTA-BP1 for BCMA Detection in Multiple Myeloma. J Med Chem. 2024 Sep 12;67 (17) :15118-15130.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-P11257/

Peptides

No Development Reported