DOTA-GPC3 targeting peptide 2

DOTA-GPC3 targeting peptide 2 is an RDC peptide. DOTA-GPC3 targeting peptide 2 consists of DOTA and GPC3 targeting peptide 2. DOTA-GPC3 targeting peptide 2 can be radiolabeled. GPC3 targeting peptide 2 (Seq30) binds to GPC3 at a Kd of 0.3 nM[1].

3066439-94-6

12352005

Glycoprotein VI; Radionuclide-Drug Conjugates (RDCs)

Antibody-drug Conjugate/ADC Related; Immunology/Inflammation

COVID-19-immunoregulation

Others

99.04

DMSO : ≥ 100 mg/mL

CN(C([C@@H](NC([C@](NC([C@](NC([C@@H](NC([C@@H](N(C([C@@H](NC([C@](N(C([C@@H](N(C(CSC[C@H](N(C([C@@H](NC(CNC1=O)=O)CC2=CN=C(C3=CC=CC=C3)C=C2)=O)C)C(N)=O)=O)C)CCCCNC(CN4CCN(CCN(CCN(CC4)CC(O)=O)CC(O)=O)CC(O)=O)=O)=O)C)([H])[C@@H](C)CC)=O)CC(O)=O)=O)C)CCC(N)=O)=O)CC5=CC=C(C=C5)C(O)=O)=O)([H])[C@@H](C)OC)=O)([H])[C@@H](C)CC)=O)CC6=CC=C(C=C6)OCC(O)=O)=O)[C@H]1CC7=CC8=C(C=CN=C8)C=C7

C107H145N21O29S

2221.48

[1]Takeru Ehara, et al. Peptide compositions targeting glypican-3 and uses thereof. WO2024252336A1. WIPO (PCT) . 2024-06-06.

Blue Ice

-20°C (Powder, sealed storage, away from moisture)

http://file.medchemexpress.com/batch_PDF/HY-W1124925/DOTA-GPC3-targeting-peptide-2-SDS-MedChemExpress.pdf

Reference compound2

No Development Reported