Dovitinib
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Potent kinase inhibitor. Inhibits FLT3 (IC50 = 1 nM), c-KIT (IC50 = 2 nM), FGFR (IC50 = 8 nM), VEGFR1/2/3 (IC50 = 10 nM), PDGFRβ (IC50 = 27 nM), and CSF-1R (IC50 = 36 nM) .1 Active in cell culture and in whole animals. Selectively blocks the growth B9 cells transformed by wild type, or activated mutant FGFR3. Induces apoptosis, or sensitizes cells to induction of apoptosis by other means in a variety of cancer cell lines.
Unconjugated
Yellow-green solid
-20°C
Beschrijving
Dovitinib Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
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