Dovitinib (TKI-258)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
405169-16-6
CHIR-258
C16061-25mg
C-Kit
Protein Tyrosine Kinase
CN1CCN (CC1) C2=CC3=C (C=C2) N=C (N3) C4=C (C5=C (C=CC=C5F) NC4=O) N
C21H21FN6O
Dovitinib (TKI258, CHIR258) is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGF-1R and HER2 in cell-free assays. Phase 4.
2 years -80 in solvent
Beschrijving
Dovitinib (TKI-258) Beschikbaar in 25 mg. Wordt geleverd met droogijs. Bestel eenvoudig online met snelle levering.
Specificaties
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