DPC-168
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
DPC-168 is an orally effective CCR3 antagonist (IC50 = 41 nM) . DPC-168 exhibits a significant ability to inhibit eosinophil chemotaxis and pulmonary inflammation. DPC-168 can be used for research on airway inflammation[1].
275810-55-4
12352005
CCR
GPCR/G Protein; Immunology/Inflammation
Inflammation/Immunology
O=C(N[C@H]1[C@H](CN2C[C@H](CC3=CC=C(F)C=C3)CCC2)CCCC1)NC4=CC=CC(C(C)=O)=C4
C28H36FN3O2
465.60
[1]D'Elios M M, et al. Interfering with chemokines and chemokine receptors as potential new therapeutic strategies[J]. Expert Opinion on Therapeutic Patents, 2008, 18 (3) : 309-325.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-19501/
Reference compound1
Phase 1
Beschrijving
DPC-168 is an orally effective CCR3 antagonist (IC50 = 41 nM) . DPC-168 exhibits a significant ability to inhibit eosinophil chemotaxis and pulmonary inflammati
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