DPP-4-IN-18
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
DPP-4-IN-18 (Sitagliptin impurity 3) (Compound 4) impurity 3 is a potent, selective and orally active DPP-4 inhibitor with an IC50 of 27 nM. DPP-4-IN-18 can effectively prevent DPP-4 from degrading glucagon-like peptide 1 (GLP-1), thereby increasing the level of active GLP-1. DPP-4-IN-18 can be used for the research of type 2 diabetes[1].
486460-31-5
Sitagliptin impurity 3
12352005
H319-H373
Dipeptidyl Peptidase
Metabolic Enzyme/Protease
Metabolic Disease
O=C(N1CC2=NN=C(C(F)(F)F)N2CC1)C[C@H](N)CC3=CC(F)=CC=C3F
C16H16F5N5O
389.32
P260-P264-P280-P305+P351+P338-P501
[1]Thornberry NA, et al. Discovery of JANUVIA (Sitagliptin), a selective dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes. Curr Top Med Chem. 2007;7 (6) :557-68.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-Z1764/
Reference compound2
No Development Reported
DPP-4
Beschrijving
DPP-4-IN-18 (Sitagliptin impurity 3) (Compound 4) impurity 3 is a potent, selective and orally active DPP-4 inhibitor with an IC50 of 27 nM. DPP-4-IN-18 can eff
Specificaties
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